Omar Bolaji Gambari built a formidable career in law and finance in the United States before becoming more publicly active in Nigeria. He began his professional journey as an Investment Analyst with Merrill Lynch in its private client group in New York. His legal career includes high-profile associations, having worked with the General Legal Division of the United Nations and the prestigious New York law firm Simpson Thacher & Bartlett. He later joined Thorgood Law Firm in New York, specializing in corporate and international business law. In this capacity, he managed the firm’s Lagos office, advising on multi-billion Naira transactions across various sectors, including Oil & Gas, Real Estate, Information Technology, and Financial Advisory.

Upon his return to Nigeria, Gambari channeled his resources into community development through the Omar Bolaji Gambari Foundation (OBG Foundation) . His philanthropic work has focused heavily on education, youth empowerment, and infrastructure across Kwara State.